The article tries to find out influence of work related issues and family related issues on work life balance. One objective of this study is reached through proper methodology. Sample size was 419. This study has multistage sampling technique to collect data from women police employees from four districts (Chennai, Coimbatore, Trichy and Salem) in Tamil Nadu. Researcher designed questionnaire is with 5 point scale in the continuum of agreeing. Reliability of this tool is 0.84 and 0.88. Multiple regression analysis was used for data analysis. The analysis found that the women police employee’s Work Related Issues and Family Related Issues does not influence on their work life balance among women police employees. It is recommended that the officers to provide improved working conditions, reduction of work load. So that work and family related issues can be minimized the interferences of personal life interference with work, work interference with personal life and work personal life enhancement.