Background: Incorporating evidence in daily working pattern is a challenge within the profession of nursing. Reasons include a general lack of awareness, absence of periodic assessments of professional skills and poor access to academic resources. This research survey was taken to assess the knowledge of nursing personnel regarding various hospital practices, its applicability in tertiary care settings, attitude towards incorporating evidence in service delivery and to assess the effectiveness of a multidisciplinary training program in improving the same. Methodology: A semi-structured questionnaire was administered to participants, before and after attending a two day workshop titled “Ensuring Quality of Nursing Services” was conducted in the month March 2015 at SGPGIMS, a tertiary care super speciality hospital in Lucknow, Uttar Pradesh. The responses were tabulated and entered into a spreadsheet and statistically analysed using online software. Results: 107 nurses attended the workshop and the response rate was 100% for the purpose of this study. 78.3% nurses were from SGPGI. Among the attendees, 74% possessed a highest qualification attained of GNM nursing. Most of the nurses had a working experience of 1 to 5 years (56.6%). Wilcoxson signed rank test between pre and post survey answers was statistically significant with a Z-score of 4.287 (p-value <0.001) and a r value indicating strong negative relationship between wrong answers pre and post workshop. Conclusion: Nurses need more skills in evaluating research before they can incorporate the best evidence into their nursing practice. Any programme which incorporates didactic lecture series is an effective approach that can be employed by nursing leaders to educate as well as motivate nurses working in different departments and in varying shifts towards enhancing patient care and safety by incorporating best available practices.