The present study was conducted to determine the efficacy of two synthetic hormones (Ovaprim and Ovulin) to producing high number of fingerlings at reduced cost. 20 matured broodstocks of Clarias gariepinus; ten males, ten females, Ovaprim and Ovulin hormones were sourced. Broodstock of the ratio one: one were used. The females weighed 1.5 kg each were hypophysized respectively. A latency period of 14hrs was observed and the males were later dissected to obtain the milt used for fertilization. The number of eggs spawned was estimated using standard formula. The result revealed that, all the females hypophysized spawned including the control. Treatment (3) gave the best fecundity, fertilization, hatchability and survival rate of 122,500 eggs, 87.41%, 93.9% and 58.9% respectively which were significantly different (p<0.05) from other treatments. The research indicated that 75% Ovaprim combine with 25% Ovulin is recommended for induce breeding in Clarias gariepinus.