Objectives: To describe identified determinants of sedentary behavior and present strategies previously suggested in order enhancing understanding about sedentary behavior and ways of reducing sitting times through promoting physical activity. Material and methods: summarizing the current state of understanding on sedentary behavior and major factors influencing people to sit too much time based on surveying previously published studies. Results: Major interpersonal, environmental and intrapersonal, individual factors that can affect or limit people not to move or to sit for extended hours in their life one of the outcome of this study. Also scholarly suggested advices and practices are scrutinized to provide summarized information on sedentary behavior and physical activity. Conclusion: Identifying relationships of sedentary behavior with health outcomes and using relevant evidence is very important to inform public health guidelines or policy strategies.