Context: Upper trapezius muscle is most commonly affected in neck pain in about two thirds of people. Aims: To compare the effectiveness of Muscle Energy Technique (MET) versus Positional Release Technique (PRT) in terms of subjective improvement in Pain, Range of Motion and Function in computer workers suffering from trapezius muscle spasm. Settings and Design: Randomized comparative study Methods and Material: All computer worker with trapezius muscle spasm was screened for inclusion and exclusion criteria. Then patient were allocated into two groups (30 subjects in each), MET+TENS and PRT+TENS by using computer generated random sampling. Outcomes were measured using Visual Analogue Scale, Neck Disability Index Score, Cervical ROM was measured using Universal Goniometer and Manual Muscle testing done for 3 sessions per week for 4weeks. Statistical analysis: Paired t-test and unpaired t-test was used to compare effectiveness of the techniques. Result: A total of 56 subjects, 26 in MET+TENS and 30 in PRT+TENS group were enrolled. VAS and NDI score reduction was seen around 74% and 80% & 50 and 55% respectively (P<0.0001). In our study ROM was increased by 3-11% & 5-16% in MET and PRT group (P<0.0001). MMT was increased by 11-16% & 18-22% in MET and PRT group (P<0.0001).Group B is superior in all respects and our result suggest concludes pain relief and Group A delayed pain relief. VAS and NDI score was valid, well-constructed, reliable, consistent and valid (r=0.94, 0.92, 0.91, alpha=0.83 and r=0.89, 0.86, 0.86, alpha=0.75, respectively). Conclusions: PRT was more statistically and clinically superior for decreasing VAS, NDI score and improving ROM and MMT. PRT showed earlier pain relief as compared to MET. So, if patient requires prompt pain relief positional release technique is the best treatment which can be offered by Physiotherapist.