This study examined the pattern of relationship between self-construal, Health and well-being. Self-construal plays an important role in defining health and well-being of an individual. In this context, the present study identifies the role of independent self-construal and interdependent self-construal in health and well-being among Hindu male and females. Social well being scale was used to measure social integration, social acceptance, social isolation, social coherence and social contribution. Sample included 150 participants selected from Hindu community. Findings of the study show significant differences between self-construal, Health and well-being. The Hindu participants displayed the presence of both kinds of self-construal i.e. independent and interdependent in equal strength. It was found that there was a significant positive relationship between the independent and interdependent self-construal. The interdependent self-construal was positively associated with health and well being. It is generally believed that modernization would greatly reduce the role of religion both at the individual as well as societal levels of functioning. Yet it is evident that even in the 21^st century the role of religion continues to be salient across all the important spheres of life; personal, social, cultural, intellectual, political and economic.