Parkinson's disease (PD) is a degenerative disorder of the central nervous system mainly affecting the motor system. Most of the symptoms in early stage movement-related which include tremors, rigidity, slowness of movement and difficulty with walking and gait. A case study of a male patient, 72 years old having parkinson’s disease was treated at National Ayurveda Research Institute for Panchakarma, Cheruthuruthy is discussed in this paper. A course of treatment of 27 days was given to the patient. The treatment protocol comprised of Abhyanga, Pathrapotala sweda, Vasthi and Shirodhara. Mahamasha taila and Mashaathmagupthaadi ksheerapaka described in the vatavyadhi prakarana were the medicines used. After 27 days course of treatment, patient got remarkable relief in the symptoms like bradykinesia, tremors of hand and also in postural instability.