The study set to investigate the challenges that face universities in the south-south Geo-political Zone in Nigeria in their globalization efforts. Five research questions were used to guide the study and five hypotheses were tested at 0.05 level of significance. Nine universities were surveyed using descriptive survey method and one thousand, eight hundred (1,800) lecturers and students were selected for the study through simple random sampling. The result yielded a co-efficient of 0.70. Data were analysed using mean statistics and z-test statistics. The findings show that the extent of teaching information technology and the literacy level of lecturers and students in Information and computer are low. The researcher recommends that Information Technology should be fully developed in these universities to enable them award Bachelors and Post-graduate degrees and adequate equipment in the laboratories for practicals.