Background: Patients with advanced chronic kidney disease (CKD), especially those on long-term dialysis, often suffer from muscle wasting and excessive fatigue. By enhancing the strength through exercising of their muscles, bones, and joints through exercising, people with CKD can improve their, people with CKD can improve their balance and coordination. This can further prevent them from falling and likewise, protect their independence as they age. Purpose: This study was to find out the effect of resisted exercise on chronic renal failure in type 2 diabetic women. Methods: Forty diabetic women with chronic renal failure was enrolled in this study, their age ranged from 55- 65 years old they were assigned into two groups of equal number: Group(A) participated in resisted exercise (40min, 2times/ week, 12weeks) in addition to medications. Group (B): controlled by their medications only. Blood creatinine and urea was measured before and after the study. Result: Resisted exercise has significant improvement in urea (decrease) and creatinine (decrease) by 9.11% 6.89% respectively. Conclusion: Resisted exercise has significant result on chronic renal failure in type 2diabetic women.