Entrepreneurship is a major factor which contributes for the industrial development and over all development of a nation. However, it has been the domain of men for a long. With the advent of change in the policies and programmes of the government after independence and the commitment of India in the International Mandates to empower women including achieving ‘Millennium Development Goals’ which includes achieving gender equality. Women hailing both from the urban and rural areas have been taking increasing interest in income generating activities, self-employment and entrepreneurship. In the process they have taken up both traditional activities like knitting, pickle making, toy making, jam and jelly as well as non-traditional activities like computer training, catering services, beauty parlour, gym etc. Women entrepreneurs in rural parts of South India are bringing about a steady and silent change in the health sector with millet-based products. Many entrepreneurs were achieved in various fields like aquaculture, eco-nutrition, honey business, food processing units and also women entrepreneurs succeeded in social media through their research. And many welfare associations joining hands with them to develop their skills through entrepreneurship programmes.